I recently received a pair of Sx RCA ICs from Grover as well. I have to caveat my comments first with the fact that I normally use a pair of Grover 'SC.' XLR ICs between preamp and amp so comparing XLR ICs to the RCAs is probably not an ideal comparison.
After inserting the Sx RCA ICs and giving them a couple days break in revealed a cable that seems a bit of a departure from Grover's house sound. While still far from being warm and cuddly, I will say that the edge has been tamed. I've only spent one evening critically listening so far, but overall, I tend to agree with some of Shep's comments. They are more relaxed and quieter than the SC. cables making it easier to simply relax and listen to the music. But, I will say that I found myself missing some of the detail and definition that Grover's ICs have always been known for. To be honest, I have not had nearly enough time with the Sx to say anything more than brief observation, but when I swapped back in the 'SC.' XLRs, I heard a more open and dimensional soundstage with a better sense of venue and harmonic decay. More articulation, less veil, but then I also heard the return of the 'Grover edge' on some recordings. Everything is a trade-off and I'll certainly spend more time with the Sx breaking in to see if it changes further.
As always, Grover's ICs continue to be a very good cable and excellent pricing. The new Sx is probably the biggest departure from the numerous Grover upgrades I've had (I think the SX is my 4th). If you use ICs as tone controls, I could easily see how both the 'SC' series and the 'SX' series could be good fits for different challenges. But as others have said, it's all about synergy.