It's been my experience that you need truly silent PC's in the listening room. While this is 'quiet', you will hear it. Computer fans (no matter how small) make the kind of noise you probably wouldn't notice until they're off. Then it's like 'ahhh'. Actual silence!
I've found even with a 20db fan (at the PC), you will hear it at the listening position... and it does impact MY listening experience because my brain is dealing with it... YMMV of course.
This case and many others will do well in a variety of locations. No one will hear this in a living room with other noises.. or in a closet.. etc.
It is interesting to see MiniITX boards going into big cases. Not sure I see any advantage over a mini- or micro-atx if the case has drive bays and such. In fact, seems like you'd have more options going that way.