Question: Do transformers in the conditioners have an adverse affect on sound?
No. You already have transformer in this role, your power transformer. As any hardened magnetics addict will admit, more magnetics are always better! Any transformer power conditioner will do a few positive things: filter out high frequency noise from the mains, provide large reservoir of energy in magnetic form, reduce source impedance of the power (so says Torus.)
If your power conditioner is also a balanced power converter, then you add the benefit of reducing common mode noise in the system and have a quieter floating ground, as well as the above advantages of any transformer. Read some of the equitech papers for better explanation than I can remember. The disadvantage with the large transformers is they hum very softly, but if you require dead silence then you need to isolate it mechanically and acoustically.
The regens are great too, as long as they have enough power. I would buy a PurePower unit in a heartbeat. It powered some of the best bass I've ever heard with Legacy Focus SE and Edge 400W stereo amp.